Tuesday, July 7, 2015

Neuro-Behcet's or multiple sclerosis? Articles that may help with diagnosis


Is your doctor trying to decide whether your symptoms and test results show neuro-BD, or whether they're from MS instead? Here are some links to articles that may help. They give info on MRI results and other test results that can aid diagnosis. You may want to have a medical dictionary with you -- or at least a diagram of the parts of the brain -- while you look at these articles:

(1) Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria http://onlinelibrary.wiley.com/doi/10.1002/ana.22366/epdf
(See Tables 1-4 in the blue boxes for a summary of the info)

(2) Diagnosis and management of neuro-Behcet's disease: international consensus recommendations (2014)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155170/pdf/415_2013_Article_7209.pdf
(Look at pages 6-14 for the final recommendations. The first 5 pages talk about how the researchers chose the symptoms and results to include in their recommendations.)

(3) Radiological findings in Behcet disease (2015)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449986/pdf/PAMJ-20-51.pdf

(4) Technetium-99m-HMPAO SPECT and MRI of brain in patients with neuro-Behcet's syndrome (1998) 
http://jnm.snmjournals.org/content/39/10/1707.full.pdf
(Shows how SPECT imaging can show brain lesions in some neuro-BD patients, even when their MRIs are normal.)

(5) Brain imaging in multiple sclerosis (2014) 
http://emedicine.medscape.com/article/342254-overview
(Includes info on MRI, CT, and ultrasound imaging of the brain.)

(6) Radiology of multiple sclerosis (2000)
http://eradiology.bidmc.harvard.edu/LearningLab/central/bachiller.pdf
(Powerpoint presentation)

If you have a copy of "Essential Guide to Behcet's Disease" (2003), Chapter 3 covers the similarities and differences between BD and several other diseases (including MS).

You can see the most *recent* book's table of contents here: bit.ly/1vgpeNM