Wednesday, March 11, 2009

Six more abstracts & 4 free articles about Behcet's

1)  Korean J Gastroenterol. 2009 Feb;53(2):106-10.
Serial Episodes of Gastric and Cecal Perforation in a Patient with Behcet's
Disease Involving the Whole Gastrointestinal Tract: A Case Report.

Shin DY, Cheon JH, Park JJ, Kim H, Kim TI, Lee YC, Kim NK, Kim WH.
Full article is available for free at:

2) Ann Intern Med. 2008 Aug 19;149(4):284-6.
Resistant Behçet disease responsive to anakinra [Kineret].
Botsios C, Sfriso P, Furlan A, Punzi L, Dinarello CA.
Full article is available for free at:

3) Headache. 2009 Mar;49(3):467-70.
The Presentation of Headache in Neuro-Behçet's Disease: A Case-Series.
Kale N, Agaoglu J, Icen M, Yazici I, Tanik O.
Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA.

4) J Korean Med Sci. 2009 Feb;24(1):52-6. Epub 2009 Feb 28.
The prevalence and clinical characteristics of esophageal involvement in patients
with Behçet's disease: a single center experience in Korea.

Yi SW, Cheon JH, Kim JH, Lee SK, Kim TI, Lee YC, Kim WH.
Full article is available for free at:

5) Clin Exp Immunol. 2008 Dec 11. [Epub ahead of print]
Clinical Immunology Review Series: An approach to the patient with recurrent
orogenital ulceration, including Behçet's syndrome.

Keogan MT.
Department of Immunology, Beaumont Hospital, Dublin, Ireland.

6) Clin Exp Dermatol. 2009 Mar;34(2):151-5.
Classifying patients with Behçet's disease for disease severity, using a
discriminating analysis method.

Polat M, Vahaboglu G, Onde U, Eksioglu M.
Department of Dermatology, Medical Faculty, Abant Izzet Baysal University, Bolu,

7) Lancet Neurol. 2009 Feb;8(2):192-204.
Neuro-Behçet's disease: epidemiology, clinical characteristics, and management.
Al-Araji A, Kidd DP.
Neurology Department, University Hospital of North Staffordshire, Stoke-on-Trent,

8) Clin Rheumatol. 2009 Mar;28(3):357-9. Epub 2008 Dec 20.
Successful treatment for sympathetic storms in a patient with neuro-Behçet's

Gono T, Murata M, Kawaguchi Y, Wakasugi D, Soejima M, Yamanaka H, Hara M.
Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho,
Shinjuku-Ku, Tokyo 162-0054, Japan.

9) Rheumatol Int. 2009 Mar;29(5):601-3. Epub 2008 Sep 26.
Behçet's disease: clinical value of the video capsule endoscopy for small
intestine examination.

Neves FS, Fylyk SN, Lage LV, Ishioka S, Goldenstein-Schainberg C, Sakai P,
Gonçalves CR.
Rheumatology Unit, University of São Paulo, Av. Dr. Arnaldo 455, 3 andar, sala
3133, Pacaembu, São Paulo, SP, CEP 01246-903, Brazil,

10) Hellenic J Cardiol. 2008 Nov-Dec;49(6):408-14.
Reduced pressure wave reflections in patients with active clinical status of
Adamantiades-Behcet disease.

Protogerou AD, Achimastos A, Vlachopoulos C, Stamatelopoulos KS, Papaioannou TG,
Papamichael CM, Aznaouridis K, Kaklamanis P, Mavrikakis M, Stefanadis C, Lekakis
Department of Clinical Therapeutics, Alexandra Hospital, Medical School National
& Kapodistrian University of Athens, Athens, Greece.
Full article is available for free at:

Monday, March 9, 2009

Stress in childhood may lead to inflammatory diseases later in life

Is there a chance that you might have had a stressful childhood before developing Behcet's? It happened to me, and who knows...maybe it happened to you, too.

Here are some abstracts and articles that can give you some more information. Two of the articles are available online for free.

1: Dube SR, Fairweather D, Pearson WS, Felitti VJ, Anda RF, Croft JB.
Cumulative childhood stress and autoimmune diseases in adults.
Psychosom Med. 2009 Feb;71(2):243-50. Epub 2009 Feb 2.
Excerpt: "Childhood traumatic stress increased the likelihood ofhospitalization with a diagnosed autoimmune disease decades into adulthood. Thesefindings are consistent with recent biological studies on the impact of earlylife stress on subsequent inflammatory responses."
PMID: 19188532

2: Jessop DS.
The fragile mind: early life stress and inflammatory disease.
Endocrinology. 2008 Jun;149(6):2724-6. No abstract available (sorry -- maybe your doctor can get a copy of this article. It may also be available at a local medical library)
PMID: 18493026

3: Danese A, Pariante CM, Caspi A, Taylor A, Poulton R.
Childhood maltreatment predicts adult inflammation in a life-course study.
Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1319-24. Epub 2007 Jan 17.
Full article available online for free, at:
PMID: 17229839

4: Pace TW, Mletzko TC, Alagbe O, Musselman DL, Nemeroff CB, Miller AH, Heim CM.
Increased stress-induced inflammatory responses in male patients with major
depression and increased early life stress.
Am J Psychiatry. 2006 Sep;163(9):1630-3.
Full article available online for free, at:
PMID: 16946190